Aphorism 120 § 120 Aphorism 120 : Therefore medicines, on which depend man’s life and death, disease and health, must be thoroughly and most carefully distinguished from one another, and for this purpose tested by careful, pure experiments on the healthy body for the purpose of ascertaining their powers and real effects, in order to…

Aphorism 119 § 119 Aphorism 119 : As certainly as every species of plant differs in its external form, mode of life and growth, in its taste and smell from every other species and genus of plant, as certainly as every mineral and salt differs from all others, in its external as well as its…

Aphorism 118 § 118 Aphorism 118 : Every medicine exhibits peculiar actions on the human frame, which are not produced in exactly the same manner by any other medicinal substance of a different kind.1 1 This fact was also perceived by the estimable A. v. Haller, who says (Preface to his Hist. stirp. helv.): Latet…

Aphorism 117 § 117 Aphorism 117 : To the latter category belong the so-called idiosyncrasies, by which are meant peculiar corporeal constitutions which, although otherwise healthy, possess a disposition to be brought into a more or less morbid state by certain things which seem to produce no impression and no change in many other individuals.1…

Aphorism 116 § 116 Aphorism 116 : Some symptoms are produced by the medicines more frequently – that is to say, in many individuals, others more rarely or in few persons, some only in very few healthy bodies.

Aphorism 115 § 115 Aphorism 115 : Among these symptoms, there occur in the case of some medicines not a few which are partially, or under certain conditions, directly opposite to other symptoms that have previously or subsequently appeared, but which are not therefore to be regarded as actual secondary action or the mere reaction…

Aphorism 114 § 114 Aphorism 114 : With the exception of these narcotic substances, in experiments with moderate doses of medicine on healthy bodies, we observe only their primary action, i.e., those symptoms wherewith the medicine deranges the health of the human being and develops in him a morbid state of longer or shorter duration.

Aphorism 113 § 113 Aphorism 113 : The only exceptions to this are the narcotic medicines. As they, in their primary action, take away sometimes the sensibility and sensation, sometimes the irritability, it frequently happens that in their secondary action, even from moderate experimental doses on healthy bodies, an increased sensibility (and a greater irritability)…

Aphorism 112 § 112 Aphorism 112 : In those older prescriptions of the often dangerous effects of medicines ingested in excessively large doses we notice certain states that were produced, not at the commencement, but towards the termination of these sad events, and which were of an exactly opposite nature to those that first appeared.…

Aphorism 111 § 111 Aphorism 111 : The agreement of my observations on the pure effects of medicines with these older ones – although they were recorded without reference to any therapeutic object, – and the very concordance of these accounts with others of the same kind by different authors must easily convince us that…